KMID : 0376419960200020157
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Chonbuk University Medical Journal 1996 Volume.20 No. 2 p.157 ~ p.164
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Cytologic and Cytochemical Study on the Human Placental Macrophages
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Abstract
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To investigate the cytologic and cytochemical charactericstics of the human placental macrophages stains were performed on the 20 cases of normal fullterm placental tissues.
@ES The results obtained were as follows;
@EN 1. Histologic examination: The macrophages in the placental villi had round or oval nuclei and were classified three types according to the cytoplasmic features. Type 1 cell was small cell with dense eosinophilic cytoplacmic margin, type 2
cell
was
large cell with many various sized vacuolated cytoplasm (Hofbauer cell), and type 3 cell was intermediate cell with eosinophilic cytoplasm and indistinct cytoplasmic margin. Most of the type 1 and 2 cells were noticed in edematous stroma and type
3
cells were observed in normal appearing stroma of the villi.
2. Histochemical examination: All placental macrophages including Hofbauer cells were not stained with any of histochemical stains for PAS, chromolipid and fat.
3. Enzyme histochemical examination: Hofbauer cells and other macrophages in placental villous stroma showed moderate to strong activities to acid phosphatase and nonspecific esterase, but they were not stained for peroxidase.
From these results, it is suggested that Hofbauer cell sand other macrophages in placental villous stroma have characteristics of resident macrophages, and morpholgically changed according to placental condition..
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KEYWORD
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